When taken CBD affects two main cannabinoid receptors in the body. There is CB1, which is primarily located in the brain and central nervous system (nerves of the brain and spinal cord) and CB2, which is located in our immune system cells, gastrointestinal tract, and peripheral nervous system (nerves extending to the rest of the body from the brain and spinal cord).
This is important because the effects of activating these receptors can be quite noticeable. For instance, some studies have found that activation of CB2 receptors can rid the brain of beta-amyloid protein – a plaque found in people with Alzheimer’s disease while activation of CB1 receptors can positively impact depression, reduce fear and paranoia, and lower intestinal inflammation and blood pressure. CB1 receptor activation can even give relief to one of the most prevalent mental disorders in the United States – anxiety.